Remote ischaemic preconditioning in patients undergoing surgery for fractured neck of femur.
Not Applicable
Withdrawn
- Conditions
- Peri-operative myocardial damageCardiovascular - Coronary heart disease
- Registration Number
- ACTRN12609001044213
- Lead Sponsor
- HRC New Zealand
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
Patients (male / female, all ethnic groups) >65yrs who present to Middlemore Hospital with a fractured neck of femur
Exclusion Criteria
Patients will be excluded if:
They do not consent, or are unable to consent to take part in the study.
They are already participating in another clinical trial.
Patients present with a second fracture and have previously been recruited to the study.
Patients have elevated pre-operative serum troponin I levels.
Patients are taking cyclsporin or K+ channel agents
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post operative electrocardiogram changes associated with ischaemia, infarction or new onset arrhythmias[Day 1 post op<br>Day 2 post op];Samples of participants blood will be analysed for serum troponin I levels (performed in a biochemical laboratory)[Day 1 post op <br>Day 2 post op]
- Secondary Outcome Measures
Name Time Method umbers of patients who present with major adverse cardiac events (acute coronary syndromes, myocardial infarction (fatal and non fatal), episodes of cardiac failure, death from cardiac causes, hospital admissions due to cardiac causes will be extracted from hospital databases/notes. The numbers of patients presenting with these events will be recorded in the study database[1 year post op]