Remote Ischaemic Preconditioning for Protection in Vascular Surgery

Not Applicable

Completed

• Conditions: Open Abdominal Aortic Aneurysm Repair (or other Intra-Abdominal Vascular Surgery Procedure); Endovascular Abdominal Aortic Aneurysm Repair; Extra-Abdominal Bypass Graft Surgery; Cardiovascular - Diseases of the vasculature and circulation including the lymphatic system; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12611001265965
• Lead Sponsor: Andre van Rij

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-12-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Patients due to undergo elective or urgent major vascular surgery at Dunedin Public Hospital (open AAA repair, EVAR, extra-abdominal bypass graft surgery).

Exclusion Criteria

No exclusion criteria

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cardiac-related clinical adverse events including (but not limited to) myocardial infarction and arrhythmias. Clinical adverse events will be assessed by standard clinical assessments performed by the primary clinician caring for the patient. If an event is suspected (e.g. MI), standard clinical investigations will be ordered as per usual practice (e.g. for MI - ECG and cardiac Troponin T blood test). All adverse events will be classified according to the Common Terminology Criteria for Adverse Events (CTCAE) and they will be recorded by the study co-ordinator.[Clinical adverse events: Any time peri-operatively, until discharge.];Cardiac Troponin T measured in plasma using a high-sensitivity assay.[Blood samples: 24 hours prior to surgery, immediately pre-surgery, 6, 12, 24, 48, 72, 96 and 120 post-surgery.]

Secondary Outcome Measures

Name	Time	Method
Renal-related clinical adverse events including (but not limited to) renal dialysis. Assessed as per cardiac-related adverse events.[Clinical adverse events: Any time peri-operatively, until discharge.];Creatinine, urea and electrolytes measured in plasma.[Blood samples: 24 hours prior to surgery, 24 and 48 hours post-surgery.]