Evaluation of the effect of RIPC (remote ischemic preconditioning) on Migraine headache

Not Applicable

Recruiting

• Conditions: Migraine.; Chronic migraine without aura, Intractable, With status migraineurs; G43.711

• Registration Number: IRCT20210212050334N3
• Lead Sponsor: Rasht University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 27 June 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patient have at least 5 headache attacks lasting 4–72 hours (without treatment or unsuccessful treatment)
Age range 18 to 50 years
Both male and female Gender
The onset of migraines before menopause
Ability of Patient to distinguish migraine headaches from other conditions
Ability to fill out questionnaire
Signed informed consent

Exclusion Criteria

Presence of underlying diseases, history of chronic diseases or kidney, liver, cardiovascular, renal, pulmonary diseases, any malignancy, autoimmunity diseases, diabetes mellitus
Convulsions
Menopause
Head and neck trauma
Existence of asthenic damage
Mental disorders and major depression according to DSM4
Botox injection in the last 6 months
Pregnancy and lactation
Severe hypertension greater than 160/90 mm / hg
Non-migraine headaches such as tension headaches that occur more than 12 times a month and cervicogenic
Drug and alcohol dependency during one year prior to the study
Rheumatism
Migraine with aura
History of off - pump surgery

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Headache intensity. Timepoint: Each time after the migraine attack (day 0 -60). Method of measurement: According to the VAS index.;Migraine-induced disability. Timepoint: Days 0 and 90. Method of measurement: According to the MIDAS index.;Time of migraine start. Timepoint: At the admission. Method of measurement: Asking from patients.;Blood CGRP level. Timepoint: Days 0and 60. Method of measurement: ELISA kit.;Blood lactate level. Timepoint: ?Days 0 and 60. Method of measurement: Blood test.

Secondary Outcome Measures

Name	Time	Method
Migraine-induced disability. Timepoint: Days 0 and 90. Method of measurement: According to the MIDAS index.