Leucine Supplementation in Young Subjects Undergoing Resistance Training

Not Applicable

Completed

• Conditions: Healthy Volunteers
• Interventions: Dietary Supplement: Placebo; Dietary Supplement: Leucine

• Registration Number: NCT02744443
• Lead Sponsor: University of Sao Paulo

Brief Summary

Leucine supplementation could be useful to support muscle anabolism. This study aims to investigate the effects of leucine supplementation on muscle mass and muscle strength in young subjects undergoing resistance training.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2015-01
• Status Verified: 2016-04
• Primary Completion: 2016-04
• Study Completion: 2016-04
• Study First Submitted: 2016-04-12
• Study First Submitted QC: 2016-04-15
• Last Update Submitted: 2016-04-15
• Study First Posted: 2016-04-20
• Last Update Posted: 2016-04-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

• training experience > 12 months
• no previous use of anabolic steroids
• no diagnosed diseases or injuries at the time of recruitment
• one-maximum repetition strength (1-RM) in leg press ≥ 3.5 and ≤ 5.0 times the body weight

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Exclusion Criteria

• use of creatine or beta-alanine supplements for the last 3 months
• use of protein or aminoacids supplements for the last 1 month
• engagement in specific dietary restrictions
• engagement in competitive sports

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo	Placebo	Placebo supplementation (alanine, 10 g/d)
Leucine	Leucine	Leucine supplementation (10 g/d)

Primary Outcome Measures

Name	Time	Method
muscle cross-sectional area	12 weeks	B-mode ultrasound

Secondary Outcome Measures

Name	Time	Method
muscle strength	12 weeks	One repetition maximum (1RM) on 45º leg press machine and Muscular Endurance Test on 45º leg press machine

Trial Locations

Locations (1)

University of Sao Paulo; 🇧🇷 Sao Paulo, Brazil