on-invasive assessment of wrist flexion deformity in Cerebral Palsy and stroke

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 40

Inclusion Criteria

Cerebral Palsy patients
Inclusion criteria
• Young patients with motor disorders resulting from Cerebral Palsy, that have an abnormal wrist posture, i.e. showing a spontaneous flexion deformity of more than 30°
• Age between 12 and 18 years ;Stroke patients
Inclusion criteria
• Patients in the subacute to chronic stage after stroke who have developed a wrist flexion deformity, i.e. showing a wrist flexion angle of more than 30° at rest.;Control subjects
Inclusion criteria
• Age- (within one year deviation per patient), sex-matched.
• Predominantly healthy.

Exclusion Criteria

Exclusion criteria CP
• A history of confounding morbidity around the wrist, e.g. fractures.
• Restricted vision (< 0.5)
• Loss of sensibility of the hand, preventing the patient from delivering the required task performance.
• Cognitive impairments preventing the patient from understanding the instructions required for the task that has to be performed.
• Other severe co- morbidity preventing patients from delivering the required task performance.
• Previous surgery on the wrist/ lower arm;Exclusion criteria stroke
• The same as for the CP patient group;Exclusion criteria control subjects
• History of previous or current neurological disorders of central origin or peripheral origin, e.g. Parkinson, Multiple Sclerosis, Stroke, nerve lesions, CRPS, plexus brachalis lesions etc.
• A history of confounding morbidity around the wrist, e.g. fractures..
• Restricted vision preventing subject from delivering the required task performance.
• Loss of sensibility of wrist, preventing from delivering the required task performance.
• Cognitive impairments preventing the subject from understanding the instructions required for the task that has to be performed.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Location of the optimal length and passive stiffness curve of the flexor<br /><br>muscles and passive stiffness under high frequency perturbations; location of<br /><br>the optimal length and passive stiffness curve of the extensor muscles; active<br /><br>stiffness during constant activity for both muscle groups; inertia of hand,<br /><br>viscosity of wrist joint under high frequency perturbations. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Passive and active range of motion of the wrist joint, neutral position of the<br /><br>wrist, maximum voluntary contraction, Zancolli score, Ashworth score, Tardieu<br /><br>score, selected tendon reflex tests</p><br>