Benefits of dexmedetomidine with spinal anesthesia in patients undergoing lower limb surgeries

Not Applicable

Completed

• Conditions: Health Condition 1: null- ASA I and II patints falling under inclusion and exclusion criteria

• Registration Number: CTRI/2018/04/013359
• Lead Sponsor: BLK Superspeciality Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-03-08
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

1. ASA I & II patient

2. Patient undergoing lower limb surgeries under subarachnoid block

Exclusion Criteria

1.Patients belonging to ASA grade III, IV and V.

2.Patients with liver and renal dysfunction.

3.Patients with cardiac dysrhythmias.

4.Patients using ARBs, calcium channel blockers.

5.Patients with body weight > 100 kg or height <150 cms.

6.Patients with contraindications for spinal anesthesia - past history of spine surgery, infection focus at back, coagulopathy hypersensitivity to local anaesthetics or deep vein thrombosis.

7.Patients with allergy to the study drugs.

8.Patients with sedative drugs consumption.

9.Patients with history of uncontrolled, labile hypertension.

10.Patients with failure of spinal block and the need for general anesthesia.

11.Pregnant females.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time required for rescue analgesiaTimepoint: Time required for rescue analgesia when NRS score is more than 3 out of 10

Secondary Outcome Measures

Name	Time	Method
pulse, BP, Respiratory rate, charecteristic of motor and sensory block, side effects includes a) Nausea b) Vomiting c) Pruritus d) Hypotension e) Bradycardia f) Respiratory depression g) Urinary retention, sedation level, incidence of shieveringTimepoint: Sedation scores <br/ ><br>would be recorded just before the initiation of surgery and thereafter, every 20 minutes during the surgery. <br/ ><br>The vital signs will be recorded every 2 minutes for 20 minutes and then every 5 minutes for the entire <br/ ><br>intra-operative period and also at the completion of the surgery. <br/ ><br>Intra and perioperative nausea and vomiting, pruritus, shivering, additive analgesia, sedation or any <br/ ><br>other side-effects recorded.