Structural changes to the airways and lungs in older asthma patients with fixed airway obstructio

Not Applicable

• Conditions: asthma; Respiratory - Asthma

• Registration Number: ACTRN12621000772842
• Lead Sponsor: Woolcock Institute of Medical Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-06-21
• Last Update Posted: 28 June 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1) Age 40-80 years
2) Physician-diagnosis of asthma
3) History of asthma medication use in the previous year
4) Willing and able to give written informed consent
5) Non smoker (no smoking for > 6 months and < 10 pack/year smoking history)

Exclusion Criteria

1) Significant cardiac disease (ischemic heart disease or arrhythmia)
2) Documented hypersensitivity to, or intolerance of, anti-cholinergic therapies
3) Significant respiratory infection or exacerbation of Asthma within the previous 6 weeks
4) Intensive Care Unit admissions in the last 12 months.
5) Other active or chronic respiratory pathologies
6) History of lung surgery
7) Unable to perform lung function testing
8) Unable to provide informed consent
9) Current enrolment in other trials
10) Women who are pregnant or attempting to get pregnant due to radiation exposure

Study & Design

• Study Type: Observational
• Study Design: Not specified