Comparison of standard method of pre-oxygenation with heated humidified high flow nasal canula (HHHFNC)for induction of anaesthesia and fiber optic nasal intubation in head and neck cancer surgery.

Recruiting

Conditions: Malignant neoplasms of lip, oral cavity and pharynx, (2) ICD-10 Condition: O||Medical and Surgical,

Brief Summary: To prevent life-threatening eventsduring induction of general anaesthesia, pre-oxygenation protocol should extendthe apnea period safely. *Fisher&paykel AIRVO2 humidification high flow system* can deliverwarm and humidified oxygen through a specially designed nasal cannula cab bedelivered through high flow nasal cannula at a rate of 60l/min. Several studieshave shown that nasal delivery of humidified oxygen to paralyzed andanaesthetized patients maintains oxygenation and achieves acceptable carbon dioxideconcentrations.

We hypothesis that an extended apneic period withpre-oxygenation via the HFNC could be more beneficial to patients undergoinggeneral anaesthesia and fibre-optic nasal intubation compared with the standardtechnique

Recruitment & Eligibility

Inclusion Criteria

Exclusion Criteria

1.Patient refusal.
2.Anticipated difficult airway 3.Mouth opening < 2 finger breadth 4.Patients who feel difficulty during HFNC will be excluded from the study.

Primary Outcome Measures

Name	Time	Method
To compare PaO2 at predefined time points	Time points will be: \| 1. Pre induction (room air) ABG \| 2. 3 minute after pre-oxygenation \| 3. 90 second after injection rocuronium \| 4. just after successful intubation

Secondary Outcome Measures

Name	Time	Method
1.Comparison in change in PaCO2 & ABG at different predefined time points.	2.Drop in Saturation during intubation

Locations (1): National cancer Institute
🇮🇳
Jhajjar, HARYANA, India
National cancer Institute
🇮🇳Jhajjar, HARYANA, India
Dr Brajesh Kumar Ratre
Principal investigator
8696156799
brajesh.ratre@gmail.com