Improvement in Memory With Plasticity-Based Adaptive Cognitive Training (IMPACT)

Posit Science Corporation1 site in 1 country487 target enrollmentJanuary 2006

ConditionsAging

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Aging
Sponsor: Posit Science Corporation
Enrollment: 487
Locations: 1
Primary Endpoint: Cognitive effects of training
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The primary objective of this study is to evaluate the effects of a computer-based training program on the memory and cognitive abilities of mature individuals undergoing healthy aging.

Detailed Description

The computer-based training program is focused on speech reception to strengthen an individual's memory for speech. This type of training program was chosen because speech perception and memory are crucial elements of human communication and losses in this area are often the first signal of overall cognitive decline. Subjects meeting eligibility criteria and providing written, informed consent are randomized to one of two 40-session, computerized training programs.

Registry

clinicaltrials.gov

Start Date

January 2006

End Date

April 2008

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Posit Science Corporation

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age 65 or older at the time of consent.
•Mini-Mental State Examination (MMSE) score of 26 or higher.
•Fluent English speaker. For the purposes of this study, fluency will be defined as living in an English speaking country and attending an English speaking school by the age of six (participants will demonstrate fluency by reading aloud a selected paragraph).
•Visual capacity adequate to read 14 point type (participants will demonstrate visual capacity by reading aloud a selected sentence).
•Adequate hearing capacity. (Participants will demonstrate by repeating a series of words spoken by the screening clinician; the words will be spoken while a view of the clinician's mouth is obstructed to prevent lip-reading.)
•Willing and able to commit to the 6-month time requirement of the entire study period with an emphasis on availability for the 8-10 week computer based training.

Exclusion Criteria

•Mini-Mental State Examination (MMSE) score of 25 or lower.
•Self-report of current diagnosis or history of major neurological illness. Specifically:
•Alzheimer's disease
•Parkinson's disease
•Multiple sclerosis
•Amyotrophic lateral sclerosis
•Self-report of current diagnosis or history of psychiatric illness. Specifically:
•Major depressive disorder
•Bipolar disorder
•Schizophrenia