Circulation and Hemodynamics in Living Donor Kidney Transplantation in Childre
Not Applicable
Recruiting
- Conditions
- <p>renal failure pediatric living donor kidney transplantation cardiac output renal perfusion</p>10029149
- Registration Number
- NL-OMON22098
- Lead Sponsor
- Radboud university medical center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
|
kinderen gepland voor niertransplantatie met levende donor in het Radboudumc |
Exclusion Criteria
|
kinderen ouder dan 14 jaar of zwaarder dan 40 kilo |
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>absolute values and changes of CO and flow in aorta, a. renalis donor kidney<br /><br>qualitative perfusion of donorkidney<br /><br>biomarker concentration in blood and urine<br /><br>pharmacon and metabolite concentration in blood</p><br>
- Secondary Outcome Measures
Name Time Method <p>-patient characteristics recipient: sex, age, weight, length, renal disease, co-morbidities, medical history, medication<br /><br>-laboratory results, e.g. renal function<br /><br>-hemodynamic parameters (blood pressure, heart rate) during the study period<br /><br>-fluid administration<br /><br>-medication (inotropes and antihypertensive drugs)<br /><br>-surgical and anesthetic record of the kidney transplantation<br /><br>-diuresis<br /><br>-number of hospital admissions first year postKT plus cause of admission<br /><br>-ICU and hospital stay after KT<br /><br>-renal graft ischaemic times (cold and warm)<br /><br>-patient and graft survival<br /><br>-postoperative complications KT</p><br>