Circulation and Hemodynamics in Living Donation of Kidney Transplantation in Childre
Recruiting
- Conditions
- donor kidney perfusion1003836010029149
- Registration Number
- NL-OMON45477
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
recipients (children; 20 persons):
1) Age between 0-17 years, bodyweight < 40 kg
2) Scheduled for living donor kidney transplantation.
3) Signed informed consent by child and/or parents. ;Donors (adults;20 persons):
1)Accepted as kidney donor for the pediatric recipient by the treating doctors.
2) Signed informed consent;Parents (2 per recipient/child)
1) signed informed consent
Exclusion Criteria
complex congenital heart disease in the acceptor (child) and refusal of informed consent
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>1)Absolute values and percentage change in CO, AoBF and transplanted renal<br /><br>artery blood flow (TxRBF) after adult-sized kidney transplantation in pediatric<br /><br>recipients.<br /><br>2) urine and serum biomarker concentrations.<br /><br>3) pharmacon and metabolite serum concentrations.<br /><br>(see page 15 research protocol)</p><br>
- Secondary Outcome Measures
Name Time Method <p>see page 16 research protocol</p><br>