Rapid Non-Invasive Brain Stimulation for OCD (oTMS)
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Stanford University
- Enrollment
- 7
- Locations
- 1
- Primary Endpoint
- Number of Patients Who Met and Exceeded Response Criteria of Yale-Brown Obsessive-Compulsive Scale.
Overview
Brief Summary
The purpose of this study is to understand how cortical stimulation affects Obsessive-Compulsive Disorder (OCD) symptoms.
Detailed Description
Obsessive-Compulsive Disorder (OCD) is a chronic and disabling disorder that costs the economy over $2 billion annually and represents a significant public health problem. This study aims to understand how cortical stimulation affects Obsessive-Compulsive Disorder
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age 18-80
- •Primary diagnosis of OCD
- •Sufficient severity of OCD symptoms
- •Capacity to provide informed consent
Exclusion Criteria
- •Psychiatric or medical conditions or medications that make participation unsafe
- •Pregnant or nursing females
- •Previous exposure to TMS or ECT
- •History of any implanted device or psychosurgery
- •Presence of metallic device or dental braces
Outcomes
Primary Outcomes
Number of Patients Who Met and Exceeded Response Criteria of Yale-Brown Obsessive-Compulsive Scale.
Time Frame: Baseline and up to two weeks
Patients given YBOCS (Yale Brown Obsessive-Compulsive Scale), a gold standard measure of obsessions and compulsions. For the YBOCS the minimum units are 0 and Maximum units on the total scale are 40. The higher the number on the YBOCS, the more severe the symptoms. Response was defined as at least a 35% reduction on the YBOCS.
Secondary Outcomes
No secondary outcomes reported
Investigators
Carolyn Rodriguez
Assistant Professor
Stanford University