Effect of perindopril on prevention of aspiration pneumonia following severe intracerebral hemorrhage (EPOCH) study
Not Applicable
- Conditions
- acute intracerebral hemorrhage
- Registration Number
- JPRN-UMIN000008222
- Lead Sponsor
- Shonan Kamakura General Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients who died within 48 hours from admission, 2) Patients whose Japan coma scale is 3-200 or more, or Glasgow coma scale is 6 or less, 3) Patients who has diagnosed pneumonia before initiating nasal-gastric tube feeding, 4) Patients who has diagnosed malignant hypertension, 5) Patients who has diagnosed congestive cardiac failure with NYHA of 3 or more, 6) Patients who has took angiotensin converting enzyme inhibitor drugs, 7) Patients who are ineligible for any other reason in the opinion of the investigator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevalence of aspiration pneumonia in acute phase
- Secondary Outcome Measures
Name Time Method Modified Rankin Scale at 90 days after stroke onset NIHSS scale at 10days after stroke onset Blood pressure Inflammation parameters Duration of antibiotics use