The impact of weight and weight loss on central insulin function in older individuals
Not Applicable
- Conditions
- OverweightOtherwise healthy
- Registration Number
- DRKS00028576
- Lead Sponsor
- niversitätsklinikum Hamburg-Eppendorf, Institut für Systemische Neurowissenschaften
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
wish to lose weight, BMI > 25 kg/m²
Exclusion Criteria
current or previous psychiatric or neurological disorders, chronic and acute physical illness including diabetes, current psychopharmacological medication as well as MR-specific exclusion criteria. No participant followed any specific diet at the start of the experiment. To exclude systematic confounds during food evaluation, severe food allergies and adherence to a vegan diet constituted further exclusion criteria.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method BMI assessment after 3-months intervention, measured via bodyweight and height
- Secondary Outcome Measures
Name Time Method Central insulin activation after 3-months intervention, measured via fMRI activation following intranasal insulin application