The Effect of Transcranial Magnetic Stimulation and Oral Ketamine Combination Treatment on severity of symptoms in Post-Traumatic Stress Disorder (TMS-OK PTSD)

Thompson Institute, University of the Sunshine Coast0 sites28 target enrollmentMarch 25, 2021

Overview

No summary available.

Registry

who.int

Start Date

March 25, 2021

End Date

November 16, 2023

Last Updated

last year

Study Type

Interventional

Sex

All

Sponsor

Thompson Institute, University of the Sunshine Coast

•Current PTSD diagnosis
•Persons (male/female/other) aged over 18 years
•Participants must be able to understand and provide consent on the Participant Information and Consent Form (PICF).
•Participants must be able to tolerate the ketamine treatment, TMS treatment/sham TMS treatment, rating scales, blood testing and urinalysis in order to remain in the study and this will be monitored on an ongoing basis, as per the methodology.

•Psychiatric conditions:
•Mania/hypomania
•Acute suicidality requiring urgent psychiatric intervention
•History of ketamine use disorder
•History of epilepsy/seizures
•Physical conditions:
•Participants who have active or inactive implants (including device leads), including deep brain stimulators, cochlear implants, and vagus nerve stimulators.
•The presence of ferrous metal pins or plates in or near the head (within 30 cm of the coil). Including: implanted electrodes/stimulators, aneurysm clips or coils, stents, or bullet fragments.
•Participants who have history of epilepsy or unexplained seizure history.
•Participants who have previously undergone TMS treatment.