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A multicenter prospective study of Taohong Siwu Decoction in the prevention and treatment of vascular calcification in patients with chronic kidney disease

Phase 1
Conditions
Chronic renal failure
Registration Number
ITMCTR2000004025
Lead Sponsor
Shuguang Hospital, affiliated to Shanghai University of Traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

(1)The signing of the informed consent.
(2)Aged 18-80 years.
(3)The patients with ckd5 of chronic renal failure were blood stasis syndrome.
(4)There were early abnormal bone metabolism or calcium and phosphorus metabolism.

Exclusion Criteria

(1)People with serious primary diseases such as heart, brain, liver and hematopoiesis.
(2)After kidney transplantation, patients with psychosis or diabetic.
(3)Patients with acute renal failure.
(4)Pregnant or lactating women.
(5)Patients who are known to be allergic to the drugs used.
(6)People who are participating in other drug clinical trials or in other clinical trials within 3 months or other drugs that have been used to control thrombus.
(7)Other circumstances in which the researcher considers it inappropriate to participate in this study.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Fibroblast Growth Factor23;Fetuin A;Vitamin D3;Pulse wave velocity;Arterial enhancement index;alkaline phosphatase;Blood phosphorus;Asymmetric-dimethylation arginine;blood calcium;Matrix Gla protein;Calcitonin;parathyroid hormone;Brachial ankle index;bone morphogenetic protein-2;Bone density;Klotho;
Secondary Outcome Measures
NameTimeMethod
Superoxide dismutase;C-reactive protein;Malondialdehyde;Interleukin-;
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