MedPath

1C70 Feasibility Study

Not Applicable
Not yet recruiting
Conditions
Amputation
Interventions
Device: 1C70
Device: Pro-Flex XC
Registration Number
NCT05628064
Lead Sponsor
Otto Bock Healthcare Products GmbH
Brief Summary

The objective of this study is to characterize the extend of 1C70 meeting the amputees needs in comparison with their everyday and a comparator foot, in regards of daily activities, mobility and balance, as well as quality of life and pain.

Detailed Description

Not available

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
20
Inclusion Criteria
  • Person is at least 18 years old.
  • Person is a unilateral transtibial amputee with stabilized residual limb.
  • Person is a K3 ambulator based on Medicare Functional Classification Level (MFCL) .
  • Person has at least 6 months experience in walking with a prosthesis.
  • Person is using an energy storage and return (ESR) foot as their primary everyday foot
  • Person has a foot size between 22 and 30.
  • Person weights with a prosthesis between 50 and 125 kg (foot size 26 - 30), or between 45 and 100 kg (foot size 22 - 25).
  • Person wears a prosthesis daily and ≥ 8 hours/day.
  • Person is able to walk at least 500 m without having to make a break.
  • Person is willing and able to independently provide informed consent.
  • Person is willing to comply with study procedures.
Exclusion Criteria
  • Person is pregnant.
  • Person is using a hydraulic foot as their primary everyday foot.
  • Person is using a sport foot (e.g., Fillauer AllPro, Ottobock Challenger, Össur Flex-Foot Cheetah) as their primary everyday foot.
  • Person is using an ESR foot with an integrated vacuum pump (e.g., Ottobock 1C62 Triton Harmony).
  • Person has conditions that would prevent participation and pose increased risk (e.g., unstable cardiovascular conditions that preclude physical activity such as walking).
  • Person falls ≥ once a week due to the reasons that are not related to prosthesis (e.g., problems with vestibular system).
  • Person is not available for study visits during planned study duration.
  • Person is participating in another study or intends to participate in another study during this study´s duration.
  • Person cannot personally provide their consent.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Pro-Flex XC to 1C70Pro-Flex XCTranstibial amputees randomized to start with Pro-Flex XC and cross over to 1C70
1C70 to Pro-Flex XC1C70Transtibial amputees randomized to start with 1C70 and cross over to Pro-Flex XC
1C70 to Pro-Flex XCPro-Flex XCTranstibial amputees randomized to start with 1C70 and cross over to Pro-Flex XC
Pro-Flex XC to 1C701C70Transtibial amputees randomized to start with Pro-Flex XC and cross over to 1C70
Primary Outcome Measures
NameTimeMethod
Highest pain reported: 1C70 vs everyday footBaseline measurement vs 2 months after fitting with 1C70

The level of pain as a highest pain during preceding 7 days reported on a 0 ("No pain at all") to 10 ("the most intense pain imaginable") scale for the following origins: residual limb, sound limb, back, shoulder \& neck area, phantom limb pain, while wearing the 1C70 foot compared to the everyday foot.

Extent of meeting amputees prosthetic foot needs: 1C70 vs everyday foot2 months after fitting with the last study feet

The extent of meeting amputees prosthetic foot needs by 1C70 as measured by a single question with a 0 to 10 scale compared to the same score for everyday foot. Higher score correspond with higher extent of meeting amputees prosthetic foot needs.

Extent of meeting amputees prosthetic foot needs: 1C70 vs comparator foot2 months after fitting with the last study feet

The extent of meeting amputees prosthetic foot needs by 1C70 as measured by a single question with a 0 to 10 scale compared to the same score for comparator foot. Higher score correspond with higher extent of meeting amputees prosthetic foot needs.

Change in patient-perceived mobility (PLUS-M) compared to baselineBaseline measurement vs 2 months after fitting with 1C70

The change from baseline perception of mobility as measured by the Prosthetic Limb Users Survey of Mobility (PLUS-M) 12-item short form. The PLUS-M questionnaire provides a T-score that ranges from 21.8 to 71.4. Higher PLUS-M scores correspond with greater mobility.

Change in patient-perceived mobility (PLUS-M) compared to the comparator foot2 months after fitting with each of the study feet

The change from baseline perception of mobility as measured by the Prosthetic Limb Users Survey of Mobility (PLUS-M) 12-item short form. The PLUS-M questionnaire provides a T-score that ranges from 21.8 to 71.4. Higher PLUS-M scores correspond with greater mobility.

Highest pain reported: 1C70 vs comparator foot2 months after fitting with each of the study feet

The level of pain as a highest pain during preceding 7 days reported on a 0 ("No pain at all") to 10 ("the most intense pain imaginable") scale for the following origins: residual limb, sound limb, back, shoulder \& neck area, phantom limb pain, while wearing the 1C70 foot compared to the coparator foot.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (6)

John+Bamberg

🇩🇪

Hannover, Germany

Zentrum für Healthcare Technology der Privaten Hochschule Göttingen (ZHT PFH)

🇩🇪

Göttingen, Germany

Pohlig Heidelberg

🇩🇪

Heidelberg, Germany

UKM ProTec

🇩🇪

Münster, Germany

Pohlig Nürnberg

🇩🇪

Nürnberg, Germany

Pohlig Traunstein

🇩🇪

Traunstein, Germany

© Copyright 2025. All Rights Reserved by MedPath