A DOUBLE-BLIND RANDOMISED CONTROLLED TRIAL ON THE EFFECT OF DEXMEDETOMIDINE ON TRACHEAL RESPONSE WHEN ADMINISTERED BY INTRANASAL DROP VERSUS NEBULISATION DURING EXTUBATION.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/11/047245
- Lead Sponsor
- Self
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients posted for elective surgeries under general anesthesia
2.American Society of Anesthesiologists (ASA) physical status I and II
3.Age: 20 â?? 60 Years
4.Surgeries with a duration of 60-120 minutes
Exclusion Criteria
1.Patients with any nasal pathologies like nasal polyp
2.Patients undergoing upper thoracic and cardiovascular surgeries.
3.History of allergy to the drugs, which will be used in the study.
4.Patients with psychiatric disorders.
5.Patients on anti-hypertensive medications
6.Pregnant women
7.Surgeries with a duration of less than 60 minutes or beyond 150 minutes
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the quality of extubation and stress response during extubation. <br/ ><br>Timepoint: 1 minute post extubation <br/ ><br>3 minutes post extubation <br/ ><br>5 minutes post extubation <br/ ><br>10 minutes post extubation <br/ ><br>15 minutes post extubation
- Secondary Outcome Measures
Name Time Method To assess the post-operative sedation score with Ramsay Sedation ScoreTimepoint: 1. At the time of arrival in post-operative room <br/ ><br>2. At 10 minutes after arrival in post-operative room <br/ ><br>3. At 20 minutes after arrival in post-operative room <br/ ><br>4. At 30 minutes after arrival in post-operative room