A clinical trial to study the effect of two drugs, dexmedetomidine and morphine to a local anaesthetic drug ropivacaine compared to using the local anaesthetic ropivacaine alone to reduce post operative pain following spine surgery.
Not Applicable
- Conditions
- Health Condition 1: M432- Fusion of spine
- Registration Number
- CTRI/2022/12/048425
- Lead Sponsor
- Dr Sandeep Dey
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. American Society of Anesthesiologists (ASA) I/II. 2. Elective thoracolumbar spinal fusion surgery. 3. Patients giving written informed consent for study.
Exclusion Criteria
1. Known allergy to study drugs.
2. Presence of severe uncontrolled renal, liver, cerebrovascular or cardiovascular disease.
3. Chronic beta blocker treatment with heart rate or preoperative HR < 50/min.
4. Patients with psychiatric illness, low GCS ( <13/15) or those unable to understand pain scores.
5. Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the total opioid consumption in the first 24-hours post-operative period between the groups.Timepoint: At the end of surgery and final evaluation after 1 year. <br/ ><br>
- Secondary Outcome Measures
Name Time Method To compare the post operative analgesia (using visual analogue scale) between the groups.Timepoint: At the end of surgery and final evaluation after 1 year.;To compare the side effect profile between the groups.Timepoint: At the end of surgery and final evaluation after 1 year.;To compare the time of the first request for rescue analgesia between the groupsTimepoint: At the end of surgery and final evaluation after 1 year.