iver function Hepatobiliary Scintigraphy Scintigraphy (HBS) in combination with Selective Internal Radiation Therapy (SIRT)

Completed

• Conditions: liver cancer; liver metastases; 10019815

• Registration Number: NL-OMON45011
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Patients with hepatocellular carcinoma or liver metastases of other primary who are referred for SIRT.
Age * 18 years.
Signed informed consent obtained prior to any study-specific procedure.

Exclusion Criteria

Age * 18 years.
Pregnancy or breastfeeding.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary endpoint of this study is defined as segmental liver function in<br /><br>treated and untreated lobes expressed as absolute value (%/min/m2) and<br /><br>percentage of total liver function 6 weeks after SIRT; and changes in total<br /><br>liver function after SIRT.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoint is the correlation of scintigraphic findings with clinical<br /><br>and biochemical parameters such as performance score, Chil-Pugh-Turcotte score<br /><br>and serologic liver function tests collected as part of the routine patient<br /><br>management. </p><br>