Comparison of Efficacy of Oral Fluconazole Versus Oral Itraconazole in the Treatment of Pityriasis Versicolor
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 106
- 试验地点
- 1
- 主要终点
- Efficacy of Treatment
研究概览
简要总结
This study compares the efficacy of two drugs, namely flucanazole and itraconazole for the treatment of a common fungal infection of skin.
详细描述
Pityriasis versicolor is a common fungal infection of the superficial skin layers. Avalible treatment options include topical and systemic drugs. fluconazole and itraconazole are commonly used systemic agents. The aim of this study is to compare the efficacy of the two systemic drugs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All cases of Pityriasis versicolor
排除标准
- •Patients with history of chronic renal or liver disease, malignancy , or undergoing any kind of chemotherapy or radiotherapy or having cardiac conduction abnormalities.
- •Patients who received any anti-fungal therapy in the last one month.
- •Pregnant or lactating women.
研究组 & 干预措施
Group A, Fluconazole group
Group A consists of patients in whom oral fluconazole is given in dose of 300mg once weekly for 2 weeks.
干预措施: Fluconazole (Drug)
Group B, Itraconazole group
Group B consists of patients in whom oral Itraconazole is given in dose of 100mg Twice for 5 days.
干预措施: Itraconazole (Drug)
结局指标
主要结局
Efficacy of Treatment
时间窗: Upto 8 weeks
Efficacy of treatment is defined by absence of scaling by naked eye examination ,absence of yellow or golden scale reflection on woods lamp examination and absence of fungal hyphae on microscopic examination.
次要结局
未报告次要终点
研究者
Hajira Amin
Doctor
Khyber Teaching Hospital