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Clinical Trials/NCT04180462
NCT04180462
Completed
Not Applicable

Randomized Controlled Trial to Evaluate an Implementation Strategy to Increase Optimal Use of HPV Vaccine in Primary Care

Washington University School of Medicine1 site in 1 country20 target enrollmentJanuary 7, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Human Papillomavirus Vaccines
Sponsor
Washington University School of Medicine
Enrollment
20
Locations
1
Primary Endpoint
Initiation of the HPV Vaccine 2-dose Series.
Status
Completed
Last Updated
last year

Overview

Brief Summary

Washington University will evaluate the effectiveness of a multi-component implementation strategy to increase use of HPV vaccine in primary care practices.

Detailed Description

The investigators at Washington University will complete a cluster-randomized trial to evaluate the effectiveness of a multi-component implementation strategy (the intervention) to increase use of the HPV vaccine according to CDC guidelines. The unit of randomization is a community-based, primary care pediatric practice. Twenty practices will be randomized into two groups, the intervention group (n=10) or a wait-list control group (n=10). The intervention will be implemented over 2-years and includes: 1) an educational video for providers; 2) audit and feedback of vaccine coverage; 3) a communication strategy; and 4) practice facilitation. The primary outcome of HPV vaccination by age 13 will be assessed at 24 months, and at 36 months to assess if change is sustained.

Registry
clinicaltrials.gov
Start Date
January 7, 2020
End Date
April 29, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Initiation of the HPV Vaccine 2-dose Series.

Time Frame: 24 months

The proportion of eligible preteens who initiate the HPV vaccine before their 13th birthday, at 24 months, post randomization

Completion of the HPV Vaccine 2-dose Series.

Time Frame: 24 months

The proportion of eligible preteens who complete the HPV vaccine before their 13th birthday, at 24 months, post randomization.

Secondary Outcomes

  • Sustainability of the Intervention Benefit for Initiation of the HPV Vaccine.(36 months)
  • Sustainability of the Intervention Benefit for Completion of the HPV Vaccine.(36 months)

Study Sites (1)

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