Covid-19 Virtual Recovery Study
- Conditions
- Covid19
- Interventions
- Behavioral: Low dose RMTBehavioral: Endurance RMT and nasal breathingBehavioral: Strength RMTBehavioral: Strength RMT and nasal breathingBehavioral: Endurance RMT
- Registration Number
- NCT04950725
- Lead Sponsor
- Mayo Clinic
- Brief Summary
The purpose of this study is to determine the effects of respiratory muscle training (RMT) and nasal breathing on patients who have been infected with the SARS-CoV2 virus and continue to have lingering symptoms.
- Detailed Description
This study will be conducted virtually and will be completed at home using a cell phone application. Study participation involves the use of a RMT device, and/or nasal breathing. The purpose of this research is to evaluate the impact of RMT and nasal breathing on chronic symptoms of COVID-19 in patients that have recovered from SARS-CoV2.
Subjects that have tested positive for the SARS-CoV2 infection and have completed a 14 to 30 day quarantine will be recruited.The RMT device will be used up to 2 times a day at a moderate intensity for 2 or 3 sets of 10 or 15 repetitions. Additionally, 2 sets of 10 nasal breathing techniques will be performed twice a day without the RMT device.
Subjects will complete several surveys examining symptoms, physical activity, cognitive function, and quality of life at baseline, 2 weeks, and 4 weeks. Subjects will also perform phonation (speaking/speech sounds) and sit to stand tests at baseline, 2 weeks, and 4 weeks. All data will be collected through the use of a cell phone application. The cell phone application will also provide subjects with the proper RMT protocol. Additionally, subjects will receive coaching and instructions on how to use the breathing device, as well as instructions on how to complete the phonation and sit to stand test.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2268
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Low respiratory muscle training Low dose RMT Low dose of RMT and fewer repetitions and use of RMT device per week Respiratory muscle training for endurance and nasal breathing Endurance RMT and nasal breathing One set of RMT with a higher number of repetitions accompanied with sets of nasal breathing Respiratory muscle training for strengthening Strength RMT Higher number of sets with a slightly lower number of repetitions per set Respiratory muscle training for strengthening and nasal breathing Strength RMT and nasal breathing Higher number of sets with a slightly lower number of repetitions per set RMT accompanied with sets of nasal breathing Respiratory muscle training for endurance Endurance RMT One set of RMT with a higher number of repetitions
- Primary Outcome Measures
Name Time Method Change in reported cognition change from baseline to 4 weeks summary score of memory, alertness, sadness, anxiety and focus getting better (1), worse (-1) or no change (0) where higher score equals more improvement
Change in Phonation time change from baseline to 4 weeks Speaking/ speech sounds
Change in number of reported COVID symptoms change from baseline to 4 weeks question asking to report presence of COVID-related symptoms
Change in reported affect of health on physical activity change from baseline to 4 weeks rating of affect from 1 affects me severely to 5 not at all affected
Change in Sit to stand executions change from baseline to 4 weeks How many times an individual can go from sitting to standing in one minute
Change in breathing difficulty change from baseline to 4 weeks rating how difficult breathing is from 1 very difficult to 5 no difficulty at all
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Mayo Clinic in Arizona
πΊπΈScottsdale, Arizona, United States