Driving Pressure and Postoperative Pulmonary Complications in Thoracic Surgery

Not Applicable

Completed

• Conditions: Diseases of the respiratory system

• Registration Number: KCT0004698
• Lead Sponsor: Samsung Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-05-31
• Last Update Posted: 12 July 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1300

Inclusion Criteria

Adults older than or equal to 19 years with American Society of Anesthesiologists physical status ???
Patient who undergoes one-lung ventilation (more than 60 minutes) for elective thoracic surgery

Exclusion Criteria

(1)The American Society of Anesthesiologists (ASA) Physical Status classification greater than or equal to 4
(2) Symptoms of heart failure (hypertension, urination, pulmonary edema, left ventricular outflow rate <45%) or preoperative vasopressors
(3)Patient who is received oxygen therapy and ventilation care
(4) large emphysema and pneumothorax
(5) pregnancy and lactation
(6) patients participating in similar studies
(7)Joint with other operation
(8)Patient who rejects being enrolled in the study
(9)Patients with elevated intracranial pressure
(10)Patients with peripheral neuropathy or blood circulation disorders
(11)Patients with hematology disease
(12)Congenital heart disease with shunt

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative pulmonary complications are defined as one or more of the following: Hypoxia: SpO2 < 90%, Requiring oxygen therapy(Facial mask, nasal prong, continuous positive airway pressure, non-invasive positive pressure breathing or high flow nasal oxygen supply between POD 2 and 7),Initial ventilator supports longer than 24 h, Re-intubation, Requiring mechanical ventilation, Tracheostomy,Pneumonia, Empyema,Atelectasis requiring bronchoscopy,Acute respiratory distress syndrome, Acute lung injury, Persistent emphysema or pneumothorax or air leak requiring chest tube for 5 days or more, Prolonged pleural effusion requiring chest tube for 5 days or more, Bronchopleural fistula, Contralateral pneumothorax, Pulmonary embolism