Comparison of two interfascial regional nerve blocks for post-operative pain relief

Not yet recruiting

• Conditions: Other disorders of kidney and ureter in diseases classified elsewhere,

• Registration Number: CTRI/2025/06/089607
• Lead Sponsor: Sir Sunderlal Hospital, IMS, BHU

Brief Summary

**AIM:** To compare the analgesic efficacy of ultrasound-guided Quadratus Lumborum block versus Erector Spinae plane block in children undergoing elective laparoscopic pyeloplasty

**Methods:** Study will be conducted after ethical approval in paediatric patients (age 2-15 year) of either sex belonging to ASA 1 or 2 class undergoing laparoscopic pyeloplasty for pelviuretric junction obstruction. Patients (total 100) will be randomly assigned into two groups:

1) Group Q: receiving anterior QL block under all aseptic precautions in a lateral position (side to be blocked upward) with 0.5 ml/kg of 0.2% ropivacaine.

2) Group E: receiving the ESP block at T10 level under all aseptic precautions placing patients in a lateral position (side to be blocked upward) with 0.5 ml/kg of 0.2% ropivacaine.

Postoperative pain will be assessed at specified intervals using the Modified Objective Pain Score (MOPS). Total number of rescue analgesia given (Inj Tramadol 1.5 mg/kg) will be noted. Any side effects like motor block, nausea, vomiting and urinary retention will also be noted.

**Objectives: Primary-** MOPS score at 12 hours

**Secondary-** 1.     MOPS score at 2, 4,8,12, 24 and 48 hrs

2.     Need of rescue analgesia in no. of dosage (Tramadol 1.5 mg/kg) in the postoperative period.

3.     Motor weakness

4.     Parent satisfaction scale under 4-point Likert scale

5.     Time to discharge

**Study Period:** 1 year

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-06-26
• Study Start: 2025-10-07

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Age group between 2 -15 years of either sex 2) Patients having Pelviureteric junction obstruction 3) Patients belonging to American Society of Anaesthesiologists physical status I and II.

Exclusion Criteria

• 1. Parent/legal guardian refusal.
• 2. Age less than 2 years or more than 15 years 3) Children with, coagulopathy/sepsis.
• 4. Obesity(body mass index more than 30 kg per square metre) 5) Those who were converted to open 6) Those who couldn’t be extubated at end of surgery 7) Major intraoperative adverse events.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of post operative analgesia over the first 24 hours after ultrasound-guided Quadratus Lumborum block versus Erector Spinae plane block	MOPS score at 0,1,2,3, 4,8,12,16, 20, 24 hours after the completion of surgery.

Secondary Outcome Measures

Name	Time	Method
MOPS score	2, 4,8,12, 24 and 48 hrs
Need of rescue analgesia in no. of dosage (Tramadol 1.5 mg/kg) in the postoperative period.
Parent satisfaction scale under 4-point Likert scale
Motor weakness
Time to discharge

Trial Locations

Locations (1)

Sir Sunderlal Hospital, BHU, Varanasi; 🇮🇳 Varanasi, UTTAR PRADESH, India

Sir Sunderlal Hospital, BHU, Varanasi

🇮🇳Varanasi, UTTAR PRADESH, India

Dr Atul Kumar Singh

Principal investigator

8317010317

atulksingh84@gmail.com