Arthroscopic Partial Meniscectomy Versus Physical Therapy for Patients Over 45 Years With a Meniscal Tears: 5-year Follow-up of the ESCAPE Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Meniscus Tear, Tibial
- Sponsor
- Onze Lieve Vrouwe Gasthuis
- Enrollment
- 321
- Primary Endpoint
- Knee Documentation Committee Subjective Knee Form (IKDC) questionnaire
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Arthroscopic partial meniscectomie (APM) offers little short-term to medium-term benefit above sham surgery or non-surgical management for knee function in most patients with a symptomatic degenerative meniscus tear. It is suggested that APM is associated with increased risk of accelerated progression of knee osteoarthritis in middle-aged to older patients.
With the 5 year follow-up of the ESCAPE trial we will investigate the longterm results of APM and physical therapy in patients with a meniscal tear over 45 years old.
Investigators
Rudolf W Poolman, MD PhD
Principal Investigator
Onze Lieve Vrouwe Gasthuis
Eligibility Criteria
Inclusion Criteria
- •45 to 70 years old MRI confirmed, non-obstructive and symptomatic meniscal tear
Exclusion Criteria
- •Knee locking or trauma leading to acute surgery;
- •▸ Associated injuries on the index knee consisting of:
- •Symptomatic partial or total tear of the anterior cruciate ligament (ACL),
- •Posterior cruciate ligament tear,
- •OA of the knee, grade 4 on the Kellgren and Lawrence Grading Scale,
- •An injury to the lateral or posterolateral ligament complex with significant laxity;
- •Previous knee surgery on the index knee (with the exception of diagnostic arthroscopy);
- •Tumour that is suspected of malignancy, detectable on MRI;
- •Obesity with a body mass index \>35;
- •American Society of Anesthesiologists (ASA) class 4 or 5 patients;
Outcomes
Primary Outcomes
Knee Documentation Committee Subjective Knee Form (IKDC) questionnaire
Time Frame: 60 months
Knee Documentation Committee Subjective Knee Form (IKDC) questionnaire to assess patient reported knee functionWe assessed knee OA on radiographs and patient reported frequency of knee pain during activities was assessed as part of the IKDC questionnaire.
Secondary Outcomes
- Radiographic Knee osteoarthritis(60 months)
- Symptomatic knee osteoarthritis (OA)(60 months)
- Patient reported knee pain during weight bearing(60 months)
- Patient reported quality of life(60 months)