The Network Pharmacology and Mechanism Analysis of Xianxiong Chengqi Decoction in Treating Hypertension with Phlegm and Blood Stasis Syndrome

Phase 1

• Conditions: Essential hypertension

• Registration Number: ITMCTR2000003139
• Lead Sponsor: Affiliated Hospital of Shandong University of TCM

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Patients who meet the level 1 hypertension diagnosis standard in China hypertension prevention and control guidelines (2010).
2. Patients who meet the diagnostic criteria of syndrome type of phlegm and blood stasis syndrome in TCM syndrome differentiation and diagnosis.
3. Patients with stable blood pressure in the past 4 weeks, who have not been treated with traditional Chinese medicine or proprietary Chinese medicine, who have not been treated with western medicine for blood pressure reduction, or who have been treated with western medicine still belong to grade 1 hypertension.
4. Patients aged between 18-75 years (including 18 years old, excluding 75 years old), regardless of gender.
5. Patients who have clear mind, can understand and independently complete the questionnaire.
6. Patients who voluntarily participate in and cooperate with doctors and can sign written informed consent.

Exclusion Criteria

1. Patients with various secondary hypertension or refractory hypertension;
2. Patients with severe primary diseases such as brain, liver, kidney and hematopoietic system.
3. Pregnant or lactating women;
4. Patients after severe trauma or major surgery;
5. Patients with psychiatric diseases, malignant tumors or tuberculosis and other infectious diseases;
6. Patients who received clinical trials of other new drugs in the past three months;
7. Patients with allergic constitution and allergic to various drugs.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
symptom score of TCM;Mean dynamic blood pressure;

Secondary Outcome Measures

Name	Time	Method
Routine stool;Renal function;ecg;Liver function;Routine urine;Routine blood;