Comparison of Palanosetron and Dexamethasone with Ondansetron and Dexamethasone for prevention of post operative nausea and vomiting in post chemotherapy patients undergoing ovarian cancer surgery receiving opioid based intravenous patient controlled analgesia

il0 个研究点目标入组 150 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•18-70 years old female patients, American Society of Anaesthesiologist class I and II, Post chemotherapy patients undergoing open ovarian cancer surgery and requiring opioid based patient controlled analgesia

•1. American Society of Anaesthesiologist class III and above,
•2. Smokers
•3. Cognitive impairment or an active psychiatric condition
•4. Patients with known liver and kidney diseases,
•5. History of a palanosetron/ ondansetron/ dexamethasone or fentanyl allergy
•6. Use of corticosteroids, psychoactive drugs or any other medication with known emetic or
•antiemetic effect within 24 hrs prior to surgery
•7. History of opioid abuse.
•Extended Exclusion Criteri
•1. Patients who will be shifted to intensive care unit on endotracheal tube for post operative mechanical ventilation

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