The Effects of Mood on Cerebral Perfusion
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 主要终点
- Regional Cerebral perfusion (ml/100g/min) during positive mood induction
研究概览
简要总结
Measuring brain perfusion is biased by a inter- and intrasubject variability, caused by physiological and lifestyle factors. In this study, the investigators want to investigate the effects of a different mood state (neutral, positive and negative mood), induced using subjects own memories, on both global and regional cerebral perfusion, measured with arterial spin labeling.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy university students
- •between 18 and 30 years old
排除标准
- •No informed consent
- •Not using hormonal contraception
- •MRI-contraindications
- •Claustrophobia
- •Pregnancy
- •Chronic diseases and chronic medication use
结局指标
主要结局
Regional Cerebral perfusion (ml/100g/min) during positive mood induction
时间窗: 2 minutes (ASL scan during mood state induction)
Effect of positive mood induction (using volunteer's own memories) on cerebral perfusion using arterial spin labeling MRI.
Regional Cerebral perfusion (ml/100g/min) after neutral mood induction
时间窗: 2 minutes (ASL scan after mood state induction)
Effect of neutral mood (using volunteer's own memories) on cerebral perfusion using arterial spin labeling MRI.
Regional Cerebral perfusion (ml/100g/min) during negative mood induction
时间窗: 2 minutes (ASL scan during mood state induction)
Effect of negative mood induction (using volunteer's own memories) on cerebral perfusion using arterial spin labeling MRI.
Regional Cerebral perfusion (ml/100g/min) during neutral mood induction
时间窗: 2 minutes (ASL scan during mood state induction)
Effect of neutral mood induction (using volunteer's own memories) on cerebral perfusion using arterial spin labeling MRI.
Regional Cerebral perfusion (ml/100g/min) after positive mood induction
时间窗: 2 minutes (ASL scan after mood state induction)
Effect of positive mood (using volunteer's own memories) on cerebral perfusion using arterial spin labeling MRI.
Regional Cerebral perfusion (ml/100g/min) after negative mood induction
时间窗: 2 minutes (ASL scan after mood state induction)
Effect of negative mood (using volunteer's own memories) on cerebral perfusion using arterial spin labeling MRI.
次要结局
未报告次要终点