The effect of pomegranate peel extract on the prevention of ventilator-associated pneumonia

Not Applicable

• Conditions: Ventilator-associated pneumonia.; ventilator-associated pneumonia; J95.851

• Registration Number: IRCT20210523051370N4
• Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 November 2021

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Patients aged 18-65 years
Having a tracheal tube
Up to 12 hours to elapse after ICU admission
Not affected by immune system disorders or lung diseases, including pneumonia, asthma, and allergic rhinitis
Having natural teeth
Not simultaneously participating in other interventional studies

Exclusion Criteria

Patients with tracheostomy tube
A history of taking antibiotics during the last two weeks
A history of allergy to chlorhexidine and herbal mouthwashes
Reintubation
Severe maxillofacial trauma
Pregnant and lactating patients
A history of malignancy and cancer
A history of head and neck radiotherapy
A history of oral mucositis and periodontal diseases
Patients with sepsis and COVID-19 in admission
Patients with COVID-19 in admission

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical Pulmonary Infection Score. According to the CPIS, a score of 6 or higher indicates mechanical ventilator-associated pneumonia. Timepoint: The assessor will check and record the Clinical Pulmonary Infection Score of all patients on first, third and fifth days. Method of measurement: Pulmonary of Infection Survey Questionnaire.