Sepsis Associated Encephalopathy in Pediatrics

Not Applicable

Terminated

• Conditions: Sepsis; Encephalopathy

• Registration Number: RBR-7ckbb5x
• Lead Sponsor: Instituto D'Or de Pesquisa e Ensino

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-07-31
• Study Start: 2021-09-08
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Terminated
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Eligible, consecutive patients, whose parents agree with their participation, by signing the Free and Informed Consent Term (ICF) and, when relevant, the child or adolescent signs the Term of Assent (TA).

Exclusion Criteria

Refusal to sign the Informed Consent Form (ICF) and / or the Term of Assent (TA); Admission for palliative care; History of exposure to drugs, toxic substances, alcohol, industrial agents, heavy metals or any substance that is recognized may cause a change in the level of consciousness, acute disease in the central nervous system with repercussions on cognitive function, such as meningoencephalitis by any agent (viruses, fungi or bacteria), demyelinating syndromes, epilepsy; Primary immunodeficiency; Cancer under chemotherapy; Chronic use (over two weeks) of immunosuppressants in the past six months Use of corticosteroids in immunosuppressive doses in the past three months Use of neuroleptic medications with cognitive repercussions, as in the case of psychiatric illnesses; These conditions will be excluded to eliminate the influence of an inflammatory response not determined by sepsis at the level of biomarkers and to reduce confounding factors in the diagnosis of SAE-Ped.

Study & Design

• Study Type: Observational
• Study Design: Not specified