Effects of prebiotic in Heart-Gut axis of heart failure patients.

Not Applicable

• Conditions: Health Condition 1: I509- Heart failure, unspecified

• Registration Number: CTRI/2023/02/050088
• Lead Sponsor: arayana Hrudayalaya

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 March 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

•Age: 18-60 years

•Have a heart failure in New York Heart Association class II and class III and class IV

•Echocardiographically verified LVEF < 40 %

•Signed informed consent and expected cooperation of the patients for the treatment

Exclusion Criteria

•Treatment with antibiotics or probiotics within the last 3 months

•Treatment with immunosuppression drugs within the last 3 months

•History of high fibre in toleration

•Malignancy of any cause, excluding basal cell sarcoma of the skin

•Severely impaired kidney function (i.e., Estimated glomerular filtration rate < 39 ml/minute /1.73 m2)

•Impaired liver function (Alanine aminotransferase > 150 U/I) or Chronic liver disease

•Ongoing Infection, including GI infection

•Inflammatory Bowel Disease

•Bowel obstruction

•Post Colectomy

•Active myocarditis, including Chagas disease

•Pregnancy and planned pregnancy

•Lactation

Study & Design

• Study Type: Interventional
• Study Design: Not specified