The effects of Chinese herbal prescription (Liang-Xue-Xiao-Feng Powder) on the residence/survival of tissue-resident memory CD8+T cells in psoriasis epidermis
Phase 1
Recruiting
- Conditions
- Psoriasis
- Registration Number
- ITMCTR2100004386
- Lead Sponsor
- Hospital of Chengdu University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
1. Meet the diagnosis of PV;
2. A diagnosis of the blood-heat syndrome;
3. Aged 18 to 70 years;
4. Voluntarily participate in this study; Ability to sign informed consent; Agree to accept the treatment.
Exclusion Criteria
1. With other skin diseases;
2. With other Severe systemic chronic wasting disease;
3. With mental disease;
4. Psoriasis of joint type, pustular type and erythrodermic type;
5. Received systemic glucocorticoids, retinoids or methotrexate medication within a month, or who received topical glucocorticoids within 2 weeks;
6. Scar diathesis;
7. Pregnant women.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method IL-22;IFN-?;CD103;Psoriasis area and severity index;IL-17A;TNF-a;CD69;
- Secondary Outcome Measures
Name Time Method epidermal thickness;Isolation and amplification of CD8 + TRM cells;Itching score;