Aerobic training at different times of day: Vascular and autonomic adaptations in hypertensive elderly

Not Applicable

Recruiting

• Conditions: Hypertension; C14.907.489

• Registration Number: RBR-27j6zg
• Lead Sponsor: Escola de Educação Física e Esporte da Universidade de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-12-06
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Men and women; age between 60 and 90 years; hypertensives receiving anti-hypertensive drugs for 4 or more months; neither receiving beta-blockers nor non-dihydropyridine calcium channel blockers; neither chronotype type; inactive or insufficiently active; available to participate in the interventions at both proposed times of day (morning and evening), not taking any hormone replacement.

Exclusion Criteria

Presence of cardiovascular diseases beyond hypertension; presence of osteomioarticular problems that unavailable to practice exercise; systolic and diastolic blood pressures higher than 160 and 105 mmHg, respectively; obesity level 2 or above; presence of diabetes with complications or receiving insulin; presence of organ-target damage; presence of complex arrhythmias and/or ischemia during exercise.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement of the endothelial function verified by the flow-mediated dilation technique (FMD) with a minimum increase of 4% in artery diameter between the initial and final evaluations;The increase of baroreflex sensitivity calculated by the slope of linear regression generated by the absolute changes in tha HR and muscular nervous sympathetic activity (MNSA) in relation to BP beat-to-beat measured during the Modified Oxford Maneuver, with minimal changes of 0.50 in the slope of HR and 0.60 in the slope of MSNA.