Effect of a 3 second inspiratory time on pattern of ventilation and sputum cleared during manual hyperinflatio

Not Applicable

Completed

• Conditions: intubation; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12608000418370
• Lead Sponsor: yndal Maxwell

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-08-25
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

intubated for at least 2 days and likely to remain so for the next 2 days

Exclusion Criteria

inability of the person approached for consent to understand English,
head injury with intracranial pressure >/= 15 cmH2O or being managed by hyperventilation,
systolic blood pressure (BP) <100 or > 180 mmHg,
mean arterial blood pressure <70 or > 110 mmHg,
heart rate <70 or >120 bpm,
on inotropic support,
pneumothorax without an intercostal catheter in situ,
subcutaneous emphysema or intercostal catheter with an air leak,
requiring positive expiratory pressure (PEEP) >/= 10 cmH2O during synchronised intermittent mandatory ventilation (SIMV),
on continous positive airway pressure (CPAP) >/= 15 cmH2O and oxygen >50%,
adult respiratory distress syndrome,
acute pulmonary oedema,
acute bronchospasm,
baseline peak inspiratory pressure > 40 cmH2O

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
wet weight sputum[end of day 2];pattern of ventilation - volume delivered, peak inspiratory pressure, peak inspiratory and expiratory flow rates, inspiratory time, inspiratory:expiratory flow rate ratio[end of day 2]

Secondary Outcome Measures

Name	Time	Method
nil[nil]