To evaluate the effect of topical ripasudil on post-operative corneal clarity following phacoemulsification surgery
- Conditions
- Health Condition 1: H598- Other intraoperative and postprocedural complications and disorders of eye and adnexa, not elsewhere classifiedHealth Condition 2: Z961- Presence of intraocular lens
- Registration Number
- CTRI/2023/02/049379
- Lead Sponsor
- Dr.Soumya S Nair
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1.AGE-40 years TO 90 years
2.Patients who have undergone phacoemulsification surgery by one of the 3 specific surgeons through clear corneal incision with in-the-bag intraocular lens and have certain predetermined parameters of cataract and intra operative findings are recruited immediately following surgery and eye pad opening
3.CDE <40 ; Intraoperative fluid used < 500ML
4.LOCS grade of cataract < NO4 NC4
5.Cases included in the study are those done by 3 specific surgeons
6.Preoperative corneal endothelial count- Above 1800
7.Preoperative NORMAL IOP[ <20 mm of hg]
1. Corneal dystrophies and other opacities or diseases precluding routine surgery
2. Complicated cataract
3. Cataract associated with glaucoma
4. Detectable posterior segment lesions
6. Irregular follow up
7. Intraoperative additional instrumentation
8. Intraoperative complications like PCR, vitreous loss
9. Allergy to any of the drugs ( timolol maleate, ripasudil)
10.Bronchial Asthma
11.Any cardiac abnormalities
12.Any patient deemed unfit by the surgeon
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the effect of topical ripasudil hydrochloride hydrate [0.4%] in the post-operative corneal clarity following phacoemulsificationTimepoint: Post-operative day 1-2; Post-operative day 7-14 ; Post-operative day 30-60
- Secondary Outcome Measures
Name Time Method To study post-operative corneal endothelial health including endothelial cell count and central corneal thickness following PhacoemulsificationTimepoint: Post-operative day 1-2; Post-operative day 7-14 ; Post-operative day 30-60