Comparing the effect of topical 1% Avy extract gel with 1% Diclofenac gel in the treatment of patients with primary knee osteoarthritis referred to orthopedic clinic
- Conditions
- Gonarthrosis.Other primary gonarthrosis Primary gonarthrosis: NOS unilateraM17.1l
- Registration Number
- IRCT2017050133740N1
- Lead Sponsor
- Vice chancellor for research center of Shahrekord University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 150
Primary osteoarthritis in at least one knee confirmed radiologicaly on a knee x-ray; Pain presence from at least 2 weeks prior to visit; Age> 45.
Exclusion criteria: Secondary osteoarthritis; Active liver or kidney disease; Peptic ulcer disease; Diabetes; Thyroid or parathyroid diseases; Coagulopathy or taking anti-coagulatory drugs; Ischemic or hemorrhagic CVA; Past history of deep vein thrombosis; Allergy to any form of anti-inflammatory agents, Acute trauma; Alcohol use; Drug abuse; Skin diseases, infection or wound on the site of the study; Corticosteroid use in any form; Using other topical agents on the site of the study; Taking oral agents effective on osteoarthritis within 10 days from the start of the study; Pregnancy; History of the site fracture; Deformities leading to osteoarthritis; Congenital joint diseases.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: Before and after intervention. Method of measurement: VAS and WOMAC questionnaires.;Morning stiffnes. Timepoint: Before and after intervention. Method of measurement: VAS and WOMAC questionnaires.;Stiffness during the day. Timepoint: Before and after intervention. Method of measurement: VAS and WOMAC questionnaires.;Physical function. Timepoint: Before and after intervention. Method of measurement: VAS and WOMAC questionnaires.
- Secondary Outcome Measures
Name Time Method