The comparison between high dose suppository Diclofenac and Pethidine in post cesarean section pain relief
- Conditions
- Post C-section pain.
- Registration Number
- IRCT20220903055861N1
- Lead Sponsor
- Alborz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 90
Full-term Pregnant women
Aside C-section indication
Full-term alive neonate
Age between 18 and 45 year
Participation consent
Patients who show an allergic reaction to the drug will be excluded from the study
History of allergy to NSAID and pethidine
Bronchial asthma
Drug addiction, alcohol abuse, opium addict or the use of any drug that impairs the perception of pain
Proctitis
Coagulopathy
Gastrointestinal tract ulcers, stomach ulcers, history of gastrointestinal bleeding
Long-term steroid treatment or continuous use of painkillers
Neurological or psychological disorders
Users of medications that interact with pethidine, such as MAO inhibitors (e.g., isocarboxazid , methylene blue, linezolid), certain pain medications (e.g., pentazocine, nalbuphine, butorphanol), seizure medications (e.g., carbamazepine, phenytoin)
Liver and kidney diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patient's pain according to visual measurement criteria. Timepoint: 2 and 6 hour after C-section. Method of measurement: Visual measurement criteria.
- Secondary Outcome Measures
Name Time Method Drowsiness. Timepoint: 2 and 6 hour after C-section. Method of measurement: Glasgow Coma Scale.;Hypotension. Timepoint: 2 and 6 hour after C-section. Method of measurement: Sphygmomanometer.;Abnormal bleeding. Timepoint: 2 and 6 hour after C-section. Method of measurement: Physical exam.;Respiratory disfunction. Timepoint: 2 and 6 hour after C-section. Method of measurement: Spirometry and clinical examination.