The effect of Melatonin and QT on complications during and after open heart surgery

Phase 3

Recruiting

• Conditions: CAD.; Atherosclerosis of coronary artery bypass graft(s), unspecified, with unstable angina pectoris; I25.700

• Registration Number: IRCT20130311012782N58
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 March 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

Age range above 40 years
Candidate for coronary artery bypass surgery
Not taking psychoactive drugs
Absence of contraindications for the administration of melatonin and Q10 (pregnancy or decision to become pregnant, breastfeeding • Seizure disorders, bleeding disorders, autoimmune diseases such as rheumatoid arthritis, lupus, MS,
High blood pressure, organ transplant, liver problems, kidney problems)
Patient consent to participate in this study.
No drug addiction

Exclusion Criteria

Need for another surgery
Pump time higher than 120 minutes
Reoperation required due to bleeding
Death of the patient before completing the study

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Occurrence of arrhythmia. Timepoint: ?During and after the pump, the first to third day of hospitalization in the intensive care unit. Method of measurement: by electrocardiography.