The effect of Melatonin on climactric symptoms and sexual disfunctio
- Conditions
- menopause.Symptoms such as flushing, sleeplessness, headache, lack of concentration, associated with menopause
- Registration Number
- IRCT201201041548N13
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 240
having general health according to the Goldberg's questionnaire; i.e., getting <23 score, Greene scale score of at least 21, being married and between 40 and 60 years old, not using vitamin supplements, not using soya, getting a score of 28 or below in female sexual function index, not having used hormone therapy during the last 3 months, not using anti-depression, tranquilizer, hypnotic, and antihypertensive drugs, being healthy after the physical examinations, amenorrhea for at least 6 months, and FSH>40. Exclusion criteria: Suffering from liver, kidney, and digestive diseases, inability to continue taking medication for any reason, unwillingness to cooperate after the beginning of the study, and showing allergic reactions to medication.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method aboratory and clinical signs of menopause. Timepoint: Before intervention,1 ,2 and 3 month after intervention. Method of measurement: –In this study, climactric symptoms were measured through Greene questionnaire and female sexual function index questionnaire was used in order to assess the subjects' sexual function. In addition, FSH and EST were measured based on the international units.
- Secondary Outcome Measures
Name Time Method Improvement of clinical symptoms. Timepoint: Before intervention,1,2 and 3 month after intervention. Method of measurement: Completed questionnaires before and during 3 months after clinical symptoms and laboratory measurements before and after intervention.