跳至主要内容
临床试验/EUCTR2009-011175-70-GB
EUCTR2009-011175-70-GB进行中(未招募)不适用

A randomised factorial trial of N-acetylcysteine prophylaxis and iso-osmolar versus low-osmolar contrast media on kidney function in patients at risk of contrast induced nephropathy following cardiac catheterisation for percutaneous coronary interventions - the CON NEC T” trial - CONNECT

iverpool Heart and Chest Hospital0 个研究点开始时间: 2009年4月16日最近更新:
相关药物

试验速览

阶段
不适用
状态
进行中(未招募)
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • eGFR < 60 ml/m (as calculated by modified MDRD equation with local laboratory correction factor)
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range

排除标准

  • 1. Patients who had coronary angiography or other procedure with contrast exposure (CTPA etc.) within 2 weeks of PCI
  • 2. Unable to consent
  • 3. Patients undergoing angiographic investigations as a prelude to planned cardiac surgery
  • 4. Cardiogenic shock
  • 5. Unlikely to attend for follow up blood tests
  • 6. Presence of non cardiac illness that might affect life expectancy
  • 7. Any previous allergic reaction to contrast media or NAC

研究者

发起方
iverpool Heart and Chest Hospital

相似试验

已完成
不适用
A randomised trial comparing two strategies for preventing kidney failure after angioplastyKidney function impairment/coronary artery disease/contrast-induced nephropathyUrological and Genital DiseasesDrug- and heavy-metal-induced tubulo-interstitial and tubular conditions
ISRCTN15027862iverpool Heart and Chest Hospital NHS Trust (UK)200
已完成
不适用
A randomised controlled study of N-Acetylcysteine in liver transplantatioSurgery: Liver transplantSurgeryLiver transplant
ISRCTN46492332Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)170
已完成
不适用
Randomised, controlled trial of N-acetylcysteine for treatment of acute exacerbations of chronic obstructive pulmonary disease.Chronic obstructive pulmonary diseaseRespiratoryPulmonary disease
ISRCTN21676344Health Research Council of New Zealand50
招募中
2 期
The Post Anaesthesia N-Acetycysteine Cognitive Evaluation trial, investigating the potential for N-Acetylcysteine to reduce cognitive dysfunction following major elective non-cardiac surgeryPost Operative Cognitive DysfunctionSurgical Stress ResponsePost Operative Mood DisorderPost surgical painAnaesthesiology - AnaestheticsMental Health - Studies of normal psychology, cognitive function and behaviourSurgery - Other surgery
ACTRN12614000411640The Geelong Hospital370
招募中
2 期
Treatment using N-acetyl cysteine (Injection) to reduce occurrence of muscle weakness and death in patients admitted with organophosphate (OP) pesticide poisoning.
CTRI/2020/09/028060Christian medical college Vellore