ACTRN12614000411640招募中2 期
Randomised controlled trial of N-Acetyl-Cysteine vs placebo for the prevention of Post Operative Cognitive Dysfunction in major elective non-cardiac surgery
The Geelong Hospital0 个研究点目标入组 370 人开始时间: 2014年4月15日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 370
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 60 Years 至 o limit（—）
- 性别
- All
入选标准
- •Patients above the age of 60 years undergoing major elective non cardiac surgery, defined as surgery expected to last at least 1 hour in duration and requiring admission to hospital.
排除标准
- •Participants will be ineligible to take part if they;
- •* Have known contraindications to NAC including allergies and concomitant nitrate therapy
- •* Are unable to comply with the requirements of informed consent or the study protocol
- •* Are already taking NAC
- •* Require subsequent procedures necessitating general anaesthesia prior to completion of testing procedures
- •* Are undergoing carotid endarterectomy, due to the high incidence of perioperative cerebrovascular accidents
- •* Experience major perioperative morbidity, or mortality, that precludes them from completing post-operative cognitive testing within the prescribed time frame.
研究者
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