An investigation of the effect of radiofrequency electric field stimulation of spinal nerves on the contents of spinal fluid in patients with chronic radicular pai

Not Applicable

Completed

• Conditions: Chronic radicular pain; Musculoskeletal Diseases; Radiculopathy

• Registration Number: ISRCTN42690092
• Lead Sponsor: Haughton Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-07-01
• Study Start: 2019-10-22
• Last Update Posted: 10 December 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Age range 18-60 years
2. Unilateral monosegmental radicular pain in the cervical or lumbosacral nerve roots
3. Symptoms consistent with MRI findings of a contained herniated disc
4. Chronic pain lasting more than 3 months
5. Failed conservative medical management for over one month (medication and physical therapy)
6. Radicular pain is the primary complaint with minimal axial pain.
7. NRS of > 3 (on 11-point NRS)

Exclusion Criteria

1. Patient refusal
2. Atypical or bilateral radicular pain patterns
3. Axial pain
4. Cognitive impairment or language barriers that could impair the patients understanding and reporting of outcomes
5. Malignancy
6. Vertebral fractures
7. Multiple sclerosis
9. Connective tissue diseases
10. Infection
11. Pregnancy or breast feeding
12. Prior spinal surgery
13. Lumbar spine interventions in the last 6 months (epidural injections or PRF)
14. Coagulation disorder or anti-coagulant treatment
15. Psychiatric disorder
16. Allergy to local anesthetics or contrast medium
17. Pre-operative NSAID, corticosteroid, methotrexate, or opioid therapy
18. Patients will be excluded from the study if appropriate nerve stimulation during the PRF procedure or pain relief (more than 50%) post DRG block are not achieved

Study & Design

• Study Type: Interventional
• Study Design: Not specified