OPTIMIzing patient selection for deep brain STimulation of the subthalamic nucleus inParkinson’s disease: the OPTIMIST study
- Conditions
- Parkinson's disease, Deep Brain Stimulation, Parkinson's disease dementia (PDD)
- Registration Number
- NL-OMON21813
- Lead Sponsor
- eiden University Medical Center, dept. of Neurology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 83
Inclusion Criteria
Age > 18 years
Diagnosis of idiopathic Parkinson's disease
Exclusion Criteria
Exclusion criteria (contra-indications) for STN-DBS:
Parkinson's disease severity: HY stage 5
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Success to STN DBS is quantified as the difference in MDS-UPDRS<br /><br>motor scores measured during an acute stimulation challenge
- Secondary Outcome Measures
Name Time Method Psychotic symptoms in the 72 hours following surgery, measured by DOS<br /><br>Global satisfaction with surgery scale<br /><br>SENS-PD composite score<br /><br>MDS-UPDRS motor score<br /><br>Cognitive decline 12 months after surgery