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Effect of two drugs on improvement of lung function after operative fixation of cervical spine: A Prospective, Double Blinded, Randomised Control Trial

Not Applicable
Completed
Conditions
Health Condition 1: O- Medical and Surgical
Registration Number
CTRI/2023/02/049969
Lead Sponsor
AIIMS
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
75
Inclusion Criteria

1.ASA I-III physical status patients

2.Who have consented to participate in the study

3.Age- 18-65 years

Exclusion Criteria

1.Chronic kidney disease

2.Chronic liver disease

3.Allergy to study drugs

4.Patients with previously diagnosed lung pathologies- COPD, Asthma, pneumonia or any other known lung pathology.

5.Obese patients

6.Patients with previous thoracic surgery

7.Chest wall deformity

8.Recent surgery under GA in last 30 days

9.Patients with associated chest injury

10.Traumatic brain injury

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To compare the lung aeration score at 24 hours post operatively.Timepoint: Just before the start of the surgery and 24 hours after the end of the surgery
Secondary Outcome Measures
NameTimeMethod
1.Length of ICU stay <br/ ><br>2.Length of hospital stay <br/ ><br>3.30 day mortality <br/ ><br>4.Incidence of tracheostomy during hospital stay <br/ ><br>5.POPC till day 7 <br/ ><br>6.Extubation on table <br/ ><br>7.Duration of mechanical ventilation <br/ ><br>8.Change in motor power from baseline (at admission) motor power at discharge <br/ ><br>Timepoint: 30 days
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