sugammadex and neostigmine for reversal of rocuronium induced muscle relaxation in patients undergoing general anaesthesia
Not Applicable
Not yet recruiting
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/09/057991
- Lead Sponsor
- ROHILKHAND MEDICAL COLLEGE
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age: 18 years to 60 years
2.Informed and written consent from patients
3.ASA grade I & II
4.Elective surgeries under general anaesthesia
Exclusion Criteria
1.Patient with suspected difficult intubation
2.Patients with neuromuscular disorders
3.Patients with known or suspected significant renal or hepatic dysfunction.
4.Allergy or contraindication to any drug affecting neuromuscular block or general anaesthesia
5.Pregnancy
6.Breastfeeding
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To compare fast and complete recovery of neuromuscular function between sugammadex and neostigmine. <br/ ><br>2.To determine post operative residual curarization incidences in both groups. <br/ ><br>3.To assess hemodynamic changes in both groups. <br/ ><br>4.To document side effects after reversal in both groups <br/ ><br>Timepoint: In 30, 60, and 120 minutes, the level of post operative residual curarization and postoperative discomfort will be evaluated. The patients will be transferred to the ward after being monitored for 2 hours for adverse symptoms such as nausea, vomiting, bradycardia, hypotension, sedation, and others. <br/ ><br>
- Secondary Outcome Measures
Name Time Method ONETimepoint: NONE