Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)

Recruiting

• Conditions: Cannabis Use; Cancer

• Registration Number: NCT07227324
• Lead Sponsor: HealthPartners Institute

Brief Summary

Through partnership with Ontracka, the HealthPartners Institute Cancer Research Center created a secure and compliant app-based technology with the ability to seamlessly collect patient-level data on symptoms, cannabis use, real-time response to cannabis consumption, and patient-reported changes in supportive care medications such as opioids and antiemetics. By joining this registry, patients will have access to expert cannabis education, dosing recommendations, and easy symptom tracking. Patients with cancer and their oncology clinicians can utilize this reliable, cancer-specific data to help them make informed decisions together about how cannabis could be incorporated into a treatment plan. To learn more and sign up, visit https://study.ontracka.com/cannabiscurious

Detailed Description

The CURIOUS project enhances the ability to seamlessly collect patient-level data on symptoms, cannabis use, real-time response to cannabis consumption, and patient-reported changes in supportive care medications such as opioids and antiemetics. Any patient interested in cannabis use can access the weblink to receive information about the CURIOUS study. An electronic version of the informed consent document will be available for them to review.

Patients interested in participating in the CURIOUS study will sign an electronic consent form on the app that describes how data will be used and stored by the HealthPartners and the Ontracka teams. They will be required to submit their name, email, and date of birth. This will automatically establish an account in the OnTracka platform and provide instruction on how to download and install the OnTracka mobile app. After patients consent to participate, they will receive access to the Ontracka app to track cannabis consumption and symptom responses as well as complete embedded validated questionnaires sent to them through the app at defined intervals; NCI PRO-CTCAE (PRO) (every other week), PROMIS Global (QOL) (every 4 weeks) and medication logs (every 4 weeks) through 12 weeks. After week 12 collection, they will complete all surveys once again in month 6 and month 12.

Study Timeline

• Study Start: 2025-08-26
• Status Verified: 2025-11
• Study First Submitted: 2025-11-10
• Study First Submitted QC: 2025-11-10
• Last Update Submitted: 2025-11-10
• Study First Posted: 2025-11-12
• Last Update Posted: 2025-11-12
• Primary Completion: 2027-04
• Study Completion: 2028-04-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• any adult aged 18 or older who is diagnosed with cancer and using cannabis

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Adherence	from enrollment to the first 90 days of study participation	Assess adherence to CURIOUS platform by determining the percentage of consented patients who access the app/survey at least once per month during the first 90 days.

Trial Locations

Locations (1)

HealthPartners Institute Cancer Research Center; 🇺🇸 Saint Louis Park, Minnesota, United States