Effect of Remote Ischemic Preconditioning on Cognitive Function After Off-Pump Coronary Artery Bypass Graft

Phase 1

• Conditions: Ischemic Heart Disease

• Registration Number: NCT00953368
• Lead Sponsor: Asan Medical Center

Brief Summary

The aim of this study is to evaluate the effects of remote ischemic preconditioning on cognitive function in patients undergoing off-pump coronary artery bypass graft.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-08
• Study First Submitted: 2009-08-05
• Study First Submitted QC: 2009-08-05
• Last Update Submitted: 2009-08-05
• Study First Posted: 2009-08-06
• Last Update Posted: 2009-08-06
• Study Start: 2009-10
• Primary Completion: 2012-03
• Study Completion: 2012-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 270

Inclusion Criteria

• Patients undergoing elective off-pump coronary artery bypass graft surgery

Exclusion Criteria

• Emergency operation
• Preoperative use of inotropic drugs or mechanical assistant device
• Ejection fraction less than 30%
• Combined operation using CPB such as valve surgery
• Previous psychiatric and neurologic disorder
• Inability to perform the cognitive function test

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
cognitive function	preoperative, 1 week and 6 months after surgery

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, University of Ulsan, College of Medicine, Asan Medical Center; 🇰🇷 Seoul, Korea, Republic of