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Hemodynamic consequences of intra arterial treatment of intracranial aneurysms using non-invasive quantitative flow measurements from arterial spin labeling techniques in high field strength MRI.

Completed
Conditions
Aneurysm
vascular distension
10002363
Registration Number
NL-OMON37854
Lead Sponsor
niversitair Medisch Centrum Groningen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

Adult patients with unruptured intracranial aneurysm, selected for elective endovascular treatment.

Exclusion Criteria

MRI- contraindications
Other known cerebrovasculair disease

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The primary parameters of the study are the regional cerebral blood flow (rCBF)<br /><br>and maps of perfusion territories of individual arteries. rCBF measurements<br /><br>will be determined on the basis of drawn region-of-interests (ROI) before and<br /><br>after intervention. In this research the extent of the effect of endovascular<br /><br>treatment on above parameters will be globally identified.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Arterial transit time (ATT) is a secondary parameter. These measurements allow<br /><br>comparison of cerebral border zones.</p><br>
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