Autobiographical Specificity

Recruiting

• Conditions: Alzheimer Disease; Memory; Frontotemporal Dementia

• Registration Number: NCT05642351
• Lead Sponsor: Nantes University Hospital

Brief Summary

Autobiographical memory is diminished in patients with Alzheimer's Disease and those with behavioral variant of frontotemporal dementia, and research has focused on the hampered ability of patients in retrieving specific memories. However, this study proposes a detailed methodology to provide a qualitative analysis of autobiographical specificity.

Detailed Description

Patients with Alzheimer's Disease and those with behavioral variant of frontotemporal dementia will be invited to retrieve autobiographical memories. Memories will be analyzed and categorized into specific, categoric, extended, or semantic autobiographical retrieval.

Study Timeline

• Study First Submitted: 2022-11-22
• Study First Submitted QC: 2022-11-30
• Study First Posted: 2022-12-08
• Status Verified: 2023-02
• Study Start: 2023-02-03
• Last Update Submitted: 2023-02-03
• Last Update Posted: 2023-02-08
• Primary Completion: 2025-02-28
• Study Completion: 2025-02-28

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• Alzheimer' disease or avioral variant of frontotemporal dementia
• No opposition from the patient to be included in the study
• For Alzheimer's patients: a score of more than 24 out of 30 on the Mini Mental State Examination (McKhann et al., 1984)

Exclusion Criteria

• Other psychiatric/neurological disorders
• Minor patients
• Adults under guardianship or protection.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Autobiographical specificity	40 minutes	We will apply the method by Raes et al. (2007) to assess whether each retrieved event refers to a: specific event, categorical event, extended event, or semantic event

Trial Locations

Locations (1)

EL HAJ Mohamad; 🇫🇷 Nantes, France